The concept of ‘mindfulness’ is increasingly used in the intercultural literature and yet so far it is largely just a heterogeneous construct with underspecified theoretical content. This paper draws on multidisciplinary perspectives to address this shortcoming and develop an integrated analysis of this important construct. It relates ‘mindfulness’ explicitly to the Relevance-theoretic concept of “manifestness”, and incorporates insights from the psychology of motivation. It uses extracts of authentic intercultural interactions to help explain and illustrate these arguments.