This unique collection of articles in honor of Marianne Mithun represents the very latest in research on language contact and language change in the Indigenous languages of the Americas. The book aims to provide new theoretical and empirical insights into how and why languages change, especially with regard to contact phenomena in languages of North America, Meso-America and South America. The individual chapters cover a broad range of topics, including sound change, morphosyntactic change, lexical semantics, grammaticalization, language endangerment, and discourse-pragmatic change.