This paper proposes the results of an inquiry on the relationship of acculturation profiles of Russian-speaking immigrants in Belgium, the duration of their stay, and their socio-economic adaptation. The data stem from a socio-psychological survey of 132 Russian-speaking (first generation) immigrants in Belgium and were processed employing latent profile analysis. Three latent groups with varying acculturation profiles were found, mainly resembling integration, assimilation, and separation. It was found that a more positive orientation towards the host society (assimilation and integration) was associated with more socio-economic adaptation; moreover, the group with an assimilation profile was more adapted than the group with an integration profile. Also, the level of socio-economic adaptation was higher for immigrants who have resided in the host country for more than five years.