This study investigates creative product descriptions (CPDs) in an intercultural context, especially with respect to cultural references (CRs) and lexical cohesion. More specifically, it examines (i) how CRs are utilized in CPDs written in English for intercultural communication, (ii) how lexical cohesion can be described in a culturally meaningful and context-sensitive way, and (iii) what role cultural reference terms play in shaping the lexical cohesion of such CPDs. By proposing a multi-layer framing model of cohesion, this paper shows how lexical cohesion results from interactions of four frames activated in the production and reception of a text: sociocultural, generic, interpersonal and conceptual. The study concludes with some practical implications for the writing of CPDs in English for intercultural communication.