This work proposes to analyze the inferences present in the metaphor in terms of the existing relations between Neuroscience and Pragmatic, describing and explanining the inferential process of such comprehension concerning the statements produced. Based on Neuroscience studies, via Coarse-code Hypothesis and Dynamic Spillover Hypothesis (PRAT et al., 2012), as well as on the theory of Relevance theory (TR) in the area of Pragmatics, the results of this research confirm that metaphor, considered in terms of this interface, can be described by Neuroscience and Pragmatic in a more complex way.