Examining the deep relations between semantic mapping and cognition by in-depth researches on the concept and essence of semantic mapping from the perspective of cognitive linguistics is of great importance. Humankind has transformed cognitive process into content presentation and by mapping conveyed ideas by word order through metaphor and inference. Chinese grammar embodies empirical and subjective principles, while English grammar logical and objective principles. The study on English and Chinese word order in terms of semantic mapping attaches abundant significance to grammatical system, second language acquisition, translation and foreign language teaching.