Starting from the distinction between globalization and internationalization, two of the concepts governing our current world, each one with its own models and consequences on universities and knowledge, this chapter discusses not only the challenges higher education faces in such context, but also what many scholars and part of the society consider a peril: the transformation of academia into an industry. As a symptomatic case of how the Old World copes with these new realities, the Spanish higher education system is broadly outlined while a special focus spots mobility as one of the most visible pillars of internationalization. Thus, the position of languages and the role played by the lingua franca in this scenario are also accounted for. In the second part of this chapter the results of a field work (a survey conducted on Romanian students in Spanish universities) will be displayed and commented upon. The respondents’ views on how communication is handled, what host institutions offer and expect, the extent to which curricula, course materials, administrative and social information are translated, students’ adapting problems or socializing preferences, are questions intended to cast some light on this complex issue. A further discussion on the University of Alicante as a host institution (after a previous approach to its internationalization aims and policies adopted so far) will complete this panoramic view on the topic of Universe-Cities and their dual nature: a universalist vocation and a duty to share knowledge with citizens.