Herman Melville’s Moby-Dick (1851) has been profusely adapted into visual media, from book illustration to painting and film. Since the publication of the 1947 Classics Illustrated Version by Louis Zansky and Albert Kanter, more than a dozen comic book adaptations of this novel have appeared in and outside of the United States. This article will focus on a single text: artist Bill Sienkiewicz’s, writer Dan Chichester’s and letterer Willie Schubert’s fourth installment of the revived Classics Illustrated series. There is much to discuss on the micro-level of media transposition from Melville’s novel to this comic book. Moreover, the Sienkiewicz version of Moby-Dick is a particularly rich and multi-layered adaptation of a literary text that can tell us much about the power of the twentieth-century graphic narrative to reshape our understanding of nineteenth-century literature.