This article deals with the difficulties inherent in the translation of specialized medical texts from French to Spanish. The author establishes comparisons between biomedical texts in English, French and Spanish from a linguistic, cultural terminological and translational point of view. He continues with an analysis of the translation problems related to the use of English loan words in the French language, and tries to illustrate some of the most important obstacles in medical translation from French to Spanish, from an academic and professional point of view.