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Sources of Variation in First Language Acquisition: Languages, contexts, and learners
Edited by Maya Hickmann †, Edy Veneziano and Harriet Jisa
[Trends in Language Acquisition Research 22] 2018
► pp. 391–408

Chapter 18
Early predictors of language development in Autism Spectrum Disorder

| Department of Psychological & Brain Sciences, Boston University
Although deficits in language are no longer considered diagnostic of Autism Spectrum Disorder (ASD), delays in language are among the earliest concerns noted by parents. By the time children with ASD enter school, their language skills vary widely from intact linguistic ability to no spoken language, though in all cases, communication is impaired and atypical. This chapter first reviews the research on the earliest behavioral and neural predictors of language in ASD based on studies that have prospectively followed infants who are at familial risk for ASD because they have an older sibling with the disorders. In the second part of the chapter research on behavioral predictors of language development in toddlers and preschoolers with ASD is presented. The gaps in the current literature and the clinical implications are discussed in the final sections.
Keywords: Autism Spectrum language, high-risk infants, impaired communication, event-related potentials, toddlers
Article outline
  • 1.Language in Autism Spectrum Disorder
    • 1.1Infants at risk for ASD
    • 1.2Development of language in infants at risk for ASD
    • 1.3Early behavioral differences in high-risk infants
    • 1.4Behavioral predictors of language
    • 1.5Neural foundations for speech in infant siblings
    • 1.6Toddlers with ASD
  • 2.Predictors of language outcomes in toddlers with ASD
  • 3.Conclusions
  • Acknowledgements
  • References
Published online: 22 February 2018
DOI logo
https://doi.org/10.1075/tilar.22.19tag
References (78)
References
American Psychiatric Association. 2013. Diagnostic and Statistical Manual of Mental Disorder, 5th edn. Arlington VA: American Psychiatric Publishing. DOI logoGoogle Scholar
Anderson, D., Lord, C., Risi, S., DiLavore, P., Shulman, C., Thurm, A., Welsh, A. & Pickles, A. 2007. Patterns of growth in verbal abilities among children with autism spectrum disorder. Journal of Consulting and Clinical Psychology 75: 594–604. DOI logoGoogle Scholar
Bhat, A., Galloway, J. & Landa, R. 2012. Relation between early motor delay and later communication delay in infants at risk for autism. Infant Behavior and Development 35: 838–846. DOI logoGoogle Scholar
Bruner, J. 1974. From communication to language. Cognition 3: 255–287. DOI logoGoogle Scholar
Capirci, O., Contaldo, A., Caselli, M. C. & Volterra, V. 2005. From action to language through gesture: A longitudinal perspective. Gesture 5: 155–177 DOI logoGoogle Scholar
Charman, T., Baron-Cohen, S., Swettenham, J., Baird, G., Drew, A. & Cox, A. 2003. Predicting language outcomes in infants with autism and pervasive developmental disorder. International Journal of Language and Communication Disorders 38: 265–285. DOI logoGoogle Scholar
Charman, T., Taylor, E., Drew, A., Cockerill, H., Brown, J. & Baird, G. 2005. Outcome at 7 years of children diagnosed with autism at age 2: Predictive validity of assessments conducted at age 2 and 3 years of age and pattern of symptom change over time. Journal of Child Psychology and Psychiatry 46: 500–513. DOI logoGoogle Scholar
Chawarska, K., Shic, F., Macari, S., Campbell, D., Young, G., Landa, R., et al. 2014. Eighteen-month predictors of later outcomes in younger siblings of children with autism spectrum disorder: A BSRC study. Journal of the American Academy of Child and Adolescent Psychiatry 53: 1317–1327. DOI logoGoogle Scholar
Christensen, D. L, Baio, J., Braun, K. V. et al. 2012. Prevalence and characteristics of Autism Spectrum Disorder among children aged 8 years: Autism and Developmental Disabilities Monitoring Network, 11 sites, United States, 2012. Morbidity and Mortality Weekly Report (MMWR) Surveill Summ 2016, 65 (No. SS-3), 1–23. DOI logoGoogle Scholar
Curtin, S. & Vouloumanos, A. 2013. Speech preference is associated with autistic-like behavior in 18-month-olds at risk for autism spectrum disorder. Journal of Autism and Developmental Disorders 43: 2114–2120. DOI logoGoogle Scholar
Dawson, G. & Bernier, R. 2013. A quarter century of progress on the early detection and treatment of autism spectrum disorder. Development and Psychopathology 25: 1455–1472. DOI logoGoogle Scholar
Droucker, D., Curtin, S. & Vouloumanos, A. 2013. Linking infant-direct speech and face preferences to language outcomes in infants at risk for autism spectrum disorder. Journal of Speech, Language, and Hearing Research 56: 567–576. DOI logoGoogle Scholar
Ellis Weismer, S. 2013. Developmental language disorders: Challenges and implications of cross-group comparisons. Folia Phoniatrica et Logopaedica 65: 68–77. DOI logoGoogle Scholar
Ellis Weismer, S. & Kover, S. 2015. Preschool language variation, growth, and predictors in children on the autism spectrum. Journal of Child Psychology and Psychiatry 56(12): 1327–37. DOI logo.Google Scholar
Ference, J. & Curtin, S. 2013. Attention to lexical stress and early vocabulary growth in 5-month-olds at risk for autism spectrum disorder. Journal of Experimental Child Psychology 116: 891–903. DOI logoGoogle Scholar
Gernsbacher, M., Sauer, E., Geve, H., Schweigert, E. & Goldsmith, H. 2008. Infant and toddler oral- and manual-motor skills predict later speech fluency in autism. Journal of Child Psychology and Psychiatry 49: 43–50. DOI logoGoogle Scholar
Giraud, J., Tomalski, P., Kushnerenko, E., Ribeiro, H., Davies, K., Charman, T. et al. 2012. Atypical audiovisual speech integration in infants at risk for autism. PLoS One 5: e36428.Google Scholar
Goldin-Meadow, S. 2014. Widening the lens: What the manual modality reveals about language, learning and cognition. Philosophical Transactions of the Royal Society of London, Series B: Biological Sciences 369(1651). DOI logo.Google Scholar
Green, J., Wan, M., Guiraud, J., Holsgrove, S., McNally, J., Slonims, V. et al. 2013. Intervention for infants at risk of developing autism: A case series. Journal of Autism and Developmental Disorders 43: 2502–2514. DOI logoGoogle Scholar
Hudry, K., Chandler, S., Bedford, R., Pasco, G., Gliga, T., Elsabbagh, M. et al. 2014. Early language profiles in infants at high-risk for autism spectrum disorders. Journal of Autism and Developmental Disorders 44: 154–167. DOI logoGoogle Scholar
Iverson, J. 2010. Multimodality in infancy: Vocal-motor and speech-gesture coordinations in typical and atypical development. Enfance 3: 257–274. DOI logoGoogle Scholar
Järvinen-Pasley, A., Wallace, G. L., Ramus, F., Happé, F. & Heaton, P. 2008. Enhanced perceptual processing of speech in autism. Developmental Science 11: 109–121. DOI logoGoogle Scholar
Johnson, M. H., Gliga, T., Jones, E. & Charman, T. 2015. Annual Research Review: Infant development, autism, and ADHD – early pathways to emerging disorders. Journal of Child Psychology and Psychiatry 56(3): 228–247. DOI logoGoogle Scholar
Jones, E. J., Gliga, T., Bedford, R., Charman, T. & Johnson, M. H. 2014. Developmental pathways to autism: A review of prospective studies of infants at risk. Neuroscience and Biobehavioral Reviews 39: 1–33. DOI logoGoogle Scholar
Kjelgaard, M. & Tager-Flusberg, H. 2001. An investigation of language impairment in autism: Implications for genetic subgroups. Language and Cognitive Processes 16: 287–308. DOI logoGoogle Scholar
Kuhl, P. 2010. Brain mechanisms in early language acquisition. Neuron 67: 713–727. DOI logoGoogle Scholar
Kuhl, P., Coffey-Corina, S., Paden D., Munson, J., Estes, A. & Dawson, G. 2013. Brain responses to words in 2-year-olds with autism predict developmental outcomes at age 6. PLoS One 8: e64967. DOI logoGoogle Scholar
Landa, R. & Garrett-Mayer, E. 2006. Development in infants with autism spectrum disorders: A prospective study. Journal of Child Psychology and Psychiatry 47: 629–638. DOI logoGoogle Scholar
Landa, R., Gross, A., Stuart, S. & Bauman, M. 2012. Latent class analysis of early developmental trajectory in baby siblings of children with autism. Journal of Child Psychology and Psychiatry 53: 986–996. DOI logoGoogle Scholar
LeBarton, E. S. & Iverson, J. M. 2013. Fine motor skill predicts expressive language in infant siblings of children with autism. Developmental Science 16: 815–827.Google Scholar
2016, Gesture development in toddlers with an older sibling with autism. International Journal of Language & Communication Disorders 51: 18–30. DOI logoGoogle Scholar
Leezenbaum, N., Campbell, S., Butler, D. & Iverson, J. 2014. Maternal verbal responses to communication of infants at low and heightened risk of autism. Autism 18: 694–703. DOI logoGoogle Scholar
Leonard, H. C., Elsabbagh, M. & Hill, E. L. & the BASIS team 2014. Early and persistent motor difficulties in infants at-risk of developing autism spectrum disorder: A prospective study. European Journal of Developmental Psychology 11: 18–35. DOI logoGoogle Scholar
Libertus, K., Sheperd, K., Ross, S. & Landa, R. 2014. Limited fine motor and grasping skills in 6-month-old infants at high risk for autism. Child Development 85: 2218–2231.Google Scholar
Luyster, R., Kadlec, M. B., Carter, A. & Tager-Flusberg, H. 2008. Language assessment and development in toddlers with autism spectrum disorders. Journal of Autism and Developmental Disorders 38: 1426–1438. DOI logoGoogle Scholar
Macari, S. L., Campbell, D., Gengoux, G. W., Saulnier, C. A., Klin, A. J. & Chawarska, K. 2012. Predicting developmental status from 12 to 24 months in infants at risk for autism spectrum disorder: A preliminary report. Journal of Autism and Developmental Disorders 42: 2636–2647. DOI logoGoogle Scholar
Messinger, D., Young, G., Ozonoff, S., Kobkins, K., Carter, A., Zwaigenbaum, L. et al. 2013. Beyond autism: A Baby Siblings Research Consortium study of high-risk children at three years of age. Journal of the American Academy of Child and Adolescent Psychiatry 52: 300–308. DOI logoGoogle Scholar
Messinger, D., Young, G., Webb, S., Ozonoff, S., Bryson, S., Carter, A., Carver, L., Charman, T., Chawarska, K., Curtin, S., Dobkins, K., Hertz-Picciotto, I., Hutman, T., Iverson, J., Landa, R., Nelson, C. A., Stone, W., Tager-Flusberg, H. & Zwaigenbaum, L. 2015. Early sex differences are not autism-specific: A Baby Siblings Research Consortium study. Molecular Autism 6: 32.Google Scholar
Mitchell, S., Brian, J., Zwaigenbaum, L., Roberts, W., Szatmari, P., Smith, I. et al. 2006. Early language and communication development of infants later diagnosed with autism spectrum disorder. Journal of Developmental and Behavioral Pediatrics 27: S69–78. DOI logoGoogle Scholar
Mullen, E. M. 1995. Mullen Scales of Early Learning. Circle Pines MN: AGS.Google Scholar
Mundy, P. & Hogan, A. 1996. Preliminary Manual for the Abridged Ealy Social and Communication Scales. Coral Gables FL: University of Miami.Google Scholar
Newschaffer, C. Croen, L., Fallin, M. D., Hertz-Picciotto, I., Nguyen, D., Lee, N. et al. 2012. Infant siblings and the investigation of autism risk factors. Journal of Neurodevelopmental Disorders 4: 7. DOI logo.Google Scholar
Nickel, L., Thatcher, A.R., Keller, F., Wozniak, R., & Iverson, J.M. 2013. Posture development in infants at heightened vs. low risk for autism spectrum disorders. Infancy, 18, 639–661. DOI logoGoogle Scholar
Norbury, C. F. 2013. Sources of variation in developmental language disorders: Evidence from eye-tracking studies of sentence production. Philosophical Transactions of The Royal Society B 369(1634). PMID 20120393. DOI logoGoogle Scholar
Ozonoff, S., Iosif, A., Baguio, F., Cook, I., Hill, M., Hutman, T. et al. 2010. A prospective study of the emergence of early behavioral signs of autism. Journal of the American Academy of Child and Adolescent Psychiatry 49: 256–266.Google Scholar
Ozonoff, S., Young, G., Belding, A., Hill, M., Hill, A., Hutman, T. et al. 2014. The broader autism phenotype in infancy: When does it emerge? Journal of the American Academy of Child and Adolescent Psychiatry 53: 398–407. DOI logoGoogle Scholar
Ozonoff, S., Young, G. S., Carter, A., Messinger, D., Yirmiya, N., Zwaigenbaum, L., et al. 2011. Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study. Pediatrics 128: e488–e495.Google Scholar
Patten, E., Belardi, K., Baranek, G., Watson, L., Labban, J. & Oller, K. 2014. Vocal patterns in infants with autism spectrum disorder: Canonical babbling status and vocalization frequency. Journal of Autism and Developmental Disorders 44: 2413–2428. DOI logoGoogle Scholar
Paul, R., Fuerst, Y., Ramsay, G., Chawarska, K. & Klin, A. 2010. Out of the mouths of babes: Vocal production in infant siblings of children with ASD. Journal of Child Psychology and Psychiatry 52: 588–598. DOI logoGoogle Scholar
Pickles, A., Simonoff, E., Conti-Ramsden, G., Falcaro, M., Simkin, Z., Charman, T. et al. 2009. Loss of language in early development of autism and specific language impairment. Journal of Child Psychology and Psychiatry 50: 843–852. DOI logoGoogle Scholar
Righi, G., Tierney, A. L., Tager-Flusberg, H. & Nelson, C. A. 2014. Functional connectivity in the first year of life in infants at risk for autism spectrum disorder: An EEG study. PLOS One 9(8): e105176. DOI logoGoogle Scholar
Rivera-Gaxiola, M., Silva-Pereyra, J. & Kuhl, P. K. 2005. Brain potentials to native and non-native speech contrasts in 7-and 11-month-old American infants. Developmental Science 8: 162–172. DOI logoGoogle Scholar
Rogers, S., Hepburn, S., Stackhouse, T. & Wehmer, E. 2003. Imitation performance in toddlers with autism and those with other developmental disorders. Journal of Child Psychology and Psychiatry 44: 763–781. DOI logoGoogle Scholar
Rogers, S., Vismara, L., Wagner, A., McCormick, C., Young, G. & Ozonoff, S. 2014. Autism treatment in the first year of life: A pilot study of Infant Start, a parent-implemented intervention for symptomatic infants. Journal of Autism and Developmental Disorders 44: 2981–2995. DOI logoGoogle Scholar
Rowe, M. & Goldin-Meadow, S. 2009. Early gesture selectively predicts later language learning. Developmental Science 12: 182–187. DOI logoGoogle Scholar
Sandin, S., Lichtenstein, P., Kuja-Halkola, R., Larsson, H., Hultman, C. & Reichenberg, A. 2014. The familial risk of autism. Journal of the American Medical Association 311: 1770–1777. DOI logoGoogle Scholar
Schreibman, L., Dawson, G., Stahmer, A., Landa, R., Rogers, S., McGee, G. et al. 2015. Naturalistic developmental behavioral interventions: Empirically validated treatments for autism spectrum disorder. Journal of Autism and Developmental Disorders 45(8): 2411–2428. DOI logoGoogle Scholar
Seery, A., Tager-Flusberg, H. & Nelson, C. A. 2014. Event-related potentials to repeated speech in 9-month-old infants at risk for autism spectrum disorder. Journal of Neurodevelopmental Disorders 6(1): 43. PMID 25937843. DOI logoGoogle Scholar
Seery, A. M., Vogel-Farley, V., Tager-Flusberg, H. & Nelson, C. A. 2013. Atypical lateralization of ERP response to native and non-native speech in infants at risk for autism spectrum disorder. Developmental Cognitive Neuroscience 5: 10–24. DOI logoGoogle Scholar
Sheinkopf, S., Iverson, J., Rinaldi, M. & Lester, B. 2012. Atypical acoustics in 6-month-old infants at risk for autism spectrum disorder. Autism Research 5: 331–339. DOI logoGoogle Scholar
Shic, F., Macari, S. & Chawarska, K. 2014. Speech disturbs face scanning in 6 month-old infants who develop autism spectrum disorder. Biological Psychiatry 75: 231–237. DOI logoGoogle Scholar
Sucksmith, E., Roth, I. & Hoekstra, R. 2011. Autistic traits below the clinical threshold: Re-examining the broader autism phenotype in the 21st century. Neuropsychological Review 21I: 360–389. DOI logoGoogle Scholar
Tager-Flusberg, H. 2010. The origins of social impairments in autism spectrum disorder: Studies of infants at risk. Neural Networks 23: 1072–1076. DOI logoGoogle Scholar
Tager-Flusberg, H., Edelson, L. & Luyster, R. 2011. Language and communication in autism spectrum disorders. In Autism Spectrum Disorders, D. Amaral, G. Dawson & D. Geschwind (eds), 172–185. Oxford: OUP.Google Scholar
Tager-Flusberg, H. & Joseph, R. M. 2003. Identifying neurocognitive phenotypes in autism. Philosophical Transactions of the Royal Society, Series B, 358: 303–314. DOI logoGoogle Scholar
Tager-Flusberg, H. & Kasari, C. 2013. Minimally verbal school-aged children with autism spectrum disorder: The neglected end of the spectrum. Autism Research 6: 468–478. DOI logoGoogle Scholar
Talbott, M. R., Nelson, C. A. & Tager-Flusberg, H. 2015a. Diary reports of concerns in mothers of infant siblings of children with autism across the first year of life. Journal of Autism and Developmental Disorders 45: 2187–2199. DOI logoGoogle Scholar
2015b. Maternal gesture use and language development in infant siblings of children with autism spectrum disorder. Journal of Autism and Developmental Disorder 45: 4–14. DOI logoGoogle Scholar
Taylor, L., Maybery, M., Grayndler, L. & Whitehouse, A. 2013. Evidence for distinct cognitive profiles in autism spectrum disorders and specific language impairment. Journal of Autism and Developmental Disorders 4(1):19–30. PMID: 23670577.Google Scholar
Thurm, A., Manwaring, S., Swineford, L. & Farmer, C. 2015. Longitudinal study of symptom severity and language in minimally verbal children with autism. Journal of Child Psychology and Psychiatry 56: 97–104. DOI logoGoogle Scholar
Toma, C., Hervas, A., Torrico, B., Balmana, N., Salgado, M., Maristany, M. et al. 2013. Analysis of two language-related genes in autism: A case-control association study of FOXP2 and CNTNAP2. Psychiatric Genetics 23: 82–85. DOI logoGoogle Scholar
Tomasello, M. 2003. Constructing a Language. Cambridge MA: Harvard University Press.Google Scholar
Tomblin, J. B. 2011. Co-morbidity of autism and SLI: Kinds, kin and complexity. International Journal of Language and Communication Disorders 46: 127–137. DOI logoGoogle Scholar
Tonge, B., Bull, K., Brereton, A. & Wilson, R. 2014. A review of evidence-based early intervention for behavioral problems in children with autism spectrum disorder: The core components of effective programs, child-focused interventions and comprehensive treatment models. Current Opinion in Psychiatry 27: 158–165. DOI logoGoogle Scholar
Williams, D., Botting, N. & Boucher, J. 2008. Language in autism and specific language impairment: Where are the links? Psychological Bulletin 134: 944–963. DOI logoGoogle Scholar
Young, G., Rogers, S., Hutman, T., Rozga, A., Sigman, M. & Ozonoff, S. 2011. Imitation from 12 to 24 months in autism and typical development: A longitudinal Rasch analysis. Developmental Psychology 47: 1565–1578. DOI logoGoogle Scholar
Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J. & Szatmari, P. 2005. Behavioral manifestations of autism in the first year of life. International Journal of Developmental Neuroscience 23: 143–152. DOI logoGoogle Scholar
Zwaigenbaum, L., Thurm., A., Stone, W., Baranek, G., Bryson, S., Iverson, J. et al. 2007. Studying the emergence of autism spectrum disorders in high-risk infants: Methodological and practical issues. Journal of Autism and Developmental Disorders 37: 466–480. DOI logoGoogle Scholar
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